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The power of E7449 to inhibit the action of human recombinant PARP1, mouse recombinant PARP2 or human recombinant TNKS1 was determined using chemiluminescent PARP or tankyrase assay kits from Trevigen, subsequent the manufacturer's Guidance.1 Chondrocytes are the most crucial cells in cartilage along with the central characteristic in cartilage deg